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Gliadin Activates HLA Class I-Restricted CD8(+) T Cells in Celiac Disease Intestinal Mucosa and Induces the Enterocyte Apoptosis
BACKGROUND & AIMS: The extensive infiltration of CD8(+) T cells in the intestinal mucosa of celiac disease (CD) patients is a hallmark of the disease. We identified a gliadin peptide (pA2) that is selectively recognized by CD8(+) T cells infiltrating intestinal mucosa of HLA-A2(+) CD patients. H...
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| Hoofdauteurs: | , , , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2008
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3319059/ https://ncbi.nlm.nih.gov/pubmed/18395083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.01.008 |
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