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ABC Transporters and their Role in Nucleoside and Nucleotide Drug Resistance

ATP-binding cassette (ABC) transporters confer drug resistance against a wide range of chemotherapeutic agents, including nucleoside and nucleotide based drugs. While nucleoside based drugs have been used for many years in the treatment of solid and hematological malignancies as well as viral and au...

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Detalhes bibliográficos
Main Authors: Fukuda, Yu, Schuetz, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319017/
https://ncbi.nlm.nih.gov/pubmed/22285911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.12.042
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