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Once Phosphorylated, Tyrosines in Carboxyl Terminus of Protein-tyrosine Kinase Syk Interact with Signaling Proteins, Including TULA-2, a Negative Regulator of Mast Cell Degranulation

Activation of the high affinity IgE-binding receptor (FcϵRI) results in the tyrosine phosphorylation of two conserved tyrosines located close to the COOH terminus of the protein-tyrosine kinase Syk. Synthetic peptides representing the last 10 amino acids of the tail of Syk with these two tyrosines e...

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Detalles Bibliográficos
Main Authors: de Castro, Rodrigo Orlandini, Zhang, Juan, Groves, Jacqueline R., Barbu, Emilia Alina, Siraganian, Reuben P.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318758/
https://ncbi.nlm.nih.gov/pubmed/22267732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.326850
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