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Mast Cell Signaling: the Role of Protein Tyrosine Kinase Syk, its Activation and Screening methods for New Pathway Participants

The aggregation by antigen of the IgE bound to its high affinity receptor on mast cells initiates a complex series of biochemical events that result in the release of inflammatory mediators. The essential role of the protein tyrosine kinase Syk has been appreciated for some time; newer results have...

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Bibliografiske detaljer
Main Authors: Siraganian, Reuben P., de Castro, Rodrigo O., Barbu, Emilia A., Zhang, Juan
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998559/
https://ncbi.nlm.nih.gov/pubmed/20696166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2010.08.006
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