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Mast Cell Signaling: the Role of Protein Tyrosine Kinase Syk, its Activation and Screening methods for New Pathway Participants

The aggregation by antigen of the IgE bound to its high affinity receptor on mast cells initiates a complex series of biochemical events that result in the release of inflammatory mediators. The essential role of the protein tyrosine kinase Syk has been appreciated for some time; newer results have...

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Detalhes bibliográficos
Main Authors: Siraganian, Reuben P., de Castro, Rodrigo O., Barbu, Emilia A., Zhang, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998559/
https://ncbi.nlm.nih.gov/pubmed/20696166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2010.08.006
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