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siRNA Screen for Phosphatases Involved in IgE-mediated Mast Cell Degranulation

Mast cells play pivotal roles in the initiation of the allergic response. To gain an understanding on the functions played by phosphatases in IgE-mediated mast cell activation, a siRNA library that targets all mouse phosphatase genes was screened in a mouse mast cell line, MMC-1. Out of 198 targets,...

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Bibliographic Details
Main Authors: Zhang, Juan, Mendoza, Mary, Guiraldelli, Michel, Barbu, Emilia Alina, Siraganian, Reuben P.
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882511/
https://ncbi.nlm.nih.gov/pubmed/20483767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0904169
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