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Intracellular Adenosine Inhibits IgE-Dependent Degranulation of Human Skin Mast Cells

PURPOSE: Adenosine (ADO) can enhance and inhibit mast cell degranulation. Potentiation of degranulation occurs at relatively low concentrations of ADO (10(−6)–10(−5) M) through triggering of A3AR, whereas, inhibition occurs at higher concentrations of ADO reportedly through triggering of A2aAR. Howe...

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Bibliografske podrobnosti
izdano v:J Clin Immunol
Main Authors: Gomez, Gregorio, Nardone, Vincent, Lotfi-Emran, Sahar, Zhao, Wei, Schwartz, Lawrence B.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429864/
https://ncbi.nlm.nih.gov/pubmed/24122028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10875-013-9950-x
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