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Recognition of Human Tumor Necrosis Factor α (TNF-α) by Therapeutic Antibody Fragment: ENERGETICS AND STRUCTURAL FEATURES
Human tumor necrosis factor α (TNF-α) exists in its functional state as a homotrimeric protein and is involved in inflammation processes and immune response of a human organism. Overproduction of TNF-α results in the development of chronic autoimmune diseases that can be successfully treated by inhi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3318754/ https://ncbi.nlm.nih.gov/pubmed/22262846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.318451 |
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