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Neurodegeneration Induced by Clustering of Sialylated Glycosylphosphatidylinositols of Prion Proteins

The transmissible spongiform encephalopathies, more commonly known as the prion diseases, are associated with the production and aggregation of disease-related isoforms of the prion protein (PrP(Sc)). The mechanisms by which PrP(Sc) accumulation causes neurodegeneration in these diseases are poorly...

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Hlavní autoři: Bate, Clive, Williams, Alun
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318732/
https://ncbi.nlm.nih.gov/pubmed/22262833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.275743
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