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Neurodegeneration Induced by Clustering of Sialylated Glycosylphosphatidylinositols of Prion Proteins
The transmissible spongiform encephalopathies, more commonly known as the prion diseases, are associated with the production and aggregation of disease-related isoforms of the prion protein (PrP(Sc)). The mechanisms by which PrP(Sc) accumulation causes neurodegeneration in these diseases are poorly...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3318732/ https://ncbi.nlm.nih.gov/pubmed/22262833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.275743 |
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