ERdj4 Protein Is a Soluble Endoplasmic Reticulum (ER) DnaJ Family Protein That Interacts with ER-associated Degradation Machinery

Protein localization within cells regulates accessibility for interactions with co-factors and substrates. The endoplasmic reticulum (ER) BiP co-factor ERdj4 is up-regulated by ER stress and has been implicated in ER-associated degradation (ERAD) of multiple unfolded secretory proteins. Several othe...

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Bibliographic Details
Main Authors: Lai, Chunwei Walter, Otero, Joel H., Hendershot, Linda M., Snapp, Erik
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318715/
https://ncbi.nlm.nih.gov/pubmed/22267725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.311290
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