ERdj4 Protein Is a Soluble Endoplasmic Reticulum (ER) DnaJ Family Protein That Interacts with ER-associated Degradation Machinery

Protein localization within cells regulates accessibility for interactions with co-factors and substrates. The endoplasmic reticulum (ER) BiP co-factor ERdj4 is up-regulated by ER stress and has been implicated in ER-associated degradation (ERAD) of multiple unfolded secretory proteins. Several othe...

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Autores principales: Lai, Chunwei Walter, Otero, Joel H., Hendershot, Linda M., Snapp, Erik
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318715/
https://ncbi.nlm.nih.gov/pubmed/22267725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.311290
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