Replicating Adenovirus-Simian Immunodeficiency Virus (SIV) Recombinant Priming and Envelope Protein Boosting Elicits Localized, Mucosal IgA Immunity in Rhesus Macaques Correlated with Delayed Acquisition following a Repeated Low-Dose Rectal SIV(mac251) Challenge

We have shown that sequential replicating adenovirus type 5 host range mutant human immunodeficiency virus/simian immunodeficiency virus (HIV/SIV) recombinant priming delivered first intranasally (i.n.) plus orally and then intratracheally (i.t.), followed by envelope protein boosting, elicits broad...

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Main Authors: Xiao, Peng, Patterson, L. Jean, Kuate, Seraphin, Brocca-Cofano, Egidio, Thomas, Michael A., Venzon, David, Zhao, Jun, DiPasquale, Janet, Fenizia, Claudio, Lee, Eun Mi, Kalisz, Irene, Kalyanaraman, Vaniambadi S., Pal, Ranajit, Montefiori, David, Keele, Brandon F., Robert-Guroff, Marjorie
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318604/
https://ncbi.nlm.nih.gov/pubmed/22345466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06812-11
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