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PALB2 Interacts with KEAP1 To Promote NRF2 Nuclear Accumulation and Function
PALB2/FANCN is mutated in breast and pancreatic cancers and Fanconi anemia (FA). It controls the intranuclear localization, stability, and DNA repair function of BRCA2 and links BRCA1 and BRCA2 in DNA homologous recombination repair and breast cancer suppression. Here, we show that PALB2 directly in...
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| Autores principales: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3318596/ https://ncbi.nlm.nih.gov/pubmed/22331464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06271-11 |
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