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PALB2 Interacts with KEAP1 To Promote NRF2 Nuclear Accumulation and Function

PALB2/FANCN is mutated in breast and pancreatic cancers and Fanconi anemia (FA). It controls the intranuclear localization, stability, and DNA repair function of BRCA2 and links BRCA1 and BRCA2 in DNA homologous recombination repair and breast cancer suppression. Here, we show that PALB2 directly in...

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Detalhes bibliográficos
Main Authors: Ma, Jianglin, Cai, Hong, Wu, Tongde, Sobhian, Bijan, Huo, Yanying, Alcivar, Allen, Mehta, Monal, Cheung, Ka Lung, Ganesan, Shridar, Kong, Ah-Ng Tony, Zhang, Donna D., Xia, Bing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318596/
https://ncbi.nlm.nih.gov/pubmed/22331464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06271-11
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