PALB2 Interacts with KEAP1 To Promote NRF2 Nuclear Accumulation and Function

PALB2/FANCN is mutated in breast and pancreatic cancers and Fanconi anemia (FA). It controls the intranuclear localization, stability, and DNA repair function of BRCA2 and links BRCA1 and BRCA2 in DNA homologous recombination repair and breast cancer suppression. Here, we show that PALB2 directly in...

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Hauptverfasser: Ma, Jianglin, Cai, Hong, Wu, Tongde, Sobhian, Bijan, Huo, Yanying, Alcivar, Allen, Mehta, Monal, Cheung, Ka Lung, Ganesan, Shridar, Kong, Ah-Ng Tony, Zhang, Donna D., Xia, Bing
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2012
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318596/
https://ncbi.nlm.nih.gov/pubmed/22331464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06271-11
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