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Mutation Analysis of Mycobacterial rpoB Genes and Rifampin Resistance Using Recombinant Mycobacterium smegmatis

Rifampin is a major drug used to treat leprosy and tuberculosis. The rifampin resistance of Mycobacterium leprae and Mycobacterium tuberculosis results from a mutation in the rpoB gene, encoding the β subunit of RNA polymerase. A method for the molecular determination of rifampin resistance in these...

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Bibliografische gegevens
Hoofdauteurs: Nakata, Noboru, Kai, Masanori, Makino, Masahiko
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318355/
https://ncbi.nlm.nih.gov/pubmed/22252831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05831-11
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