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Mutation Analysis of the Mycobacterium leprae folP1 Gene and Dapsone Resistance

Diaminodiphenylsulfone (dapsone) has long been used as a first-line drug worldwide for the treatment of leprosy. Diagnosis for dapsone resistance of Mycobacterium leprae by DNA tests would be of great clinical value, but the relationship between the nucleotide substitutions and susceptibility to dap...

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Hlavní autoři: Nakata, Noboru, Kai, Masanori, Makino, Masahiko
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028759/
https://ncbi.nlm.nih.gov/pubmed/21115799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01212-10
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