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Mutation Analysis of the Mycobacterium leprae folP1 Gene and Dapsone Resistance

Diaminodiphenylsulfone (dapsone) has long been used as a first-line drug worldwide for the treatment of leprosy. Diagnosis for dapsone resistance of Mycobacterium leprae by DNA tests would be of great clinical value, but the relationship between the nucleotide substitutions and susceptibility to dap...

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Detalhes bibliográficos
Main Authors: Nakata, Noboru, Kai, Masanori, Makino, Masahiko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028759/
https://ncbi.nlm.nih.gov/pubmed/21115799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01212-10
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