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Mutation Analysis of the Mycobacterium leprae folP1 Gene and Dapsone Resistance

Diaminodiphenylsulfone (dapsone) has long been used as a first-line drug worldwide for the treatment of leprosy. Diagnosis for dapsone resistance of Mycobacterium leprae by DNA tests would be of great clinical value, but the relationship between the nucleotide substitutions and susceptibility to dap...

詳細記述

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書誌詳細
主要な著者: Nakata, Noboru, Kai, Masanori, Makino, Masahiko
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028759/
https://ncbi.nlm.nih.gov/pubmed/21115799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01212-10
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