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In Vivo Impact of Met221 Substitution in GOB Metallo-β-Lactamase

Metallo-β-lactamases (MβLs) represent one of the main mechanisms of bacterial resistance against β-lactam antibiotics. The elucidation of their mechanism has been limited mostly by the structural diversity among their active sites. All MβLs structurally characterized so far present a Cys or a Ser re...

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Detalhes bibliográficos
Main Authors: Morán-Barrio, Jorgelina, Lisa, María-Natalia, Vila, Alejandro J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318309/
https://ncbi.nlm.nih.gov/pubmed/22252824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05418-11
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