Cross-Reactivity of Antipneumococcal Surface Protein C (PspC) Antibodies with Different Strains and Evaluation of Inhibition of Human Complement Factor H and Secretory IgA Binding via PspC

Pneumococcal surface protein C (PspC) is an important candidate for a cost-effective vaccine with broad coverage against pneumococcal diseases. Previous studies have shown that Streptococcus pneumoniae is able to bind to both human factor H (FH), an inhibitor of complement alternative pathway, and h...

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Detalhes bibliográficos
Main Authors: Moreno, Adriana T., Oliveira, Maria Leonor S., Ho, Paulo L., Vadesilho, Cintia F. M., Palma, Giovana M. P., Ferreira, Jorge M. C., Ferreira, Daniela M., Santos, Silvia R., Martinez, Marina B., Miyaji, Eliane N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318277/
https://ncbi.nlm.nih.gov/pubmed/22336290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.05706-11
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