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Cross-Reactivity of Antipneumococcal Surface Protein C (PspC) Antibodies with Different Strains and Evaluation of Inhibition of Human Complement Factor H and Secretory IgA Binding via PspC

Pneumococcal surface protein C (PspC) is an important candidate for a cost-effective vaccine with broad coverage against pneumococcal diseases. Previous studies have shown that Streptococcus pneumoniae is able to bind to both human factor H (FH), an inhibitor of complement alternative pathway, and h...

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書誌詳細
主要な著者: Moreno, Adriana T., Oliveira, Maria Leonor S., Ho, Paulo L., Vadesilho, Cintia F. M., Palma, Giovana M. P., Ferreira, Jorge M. C., Ferreira, Daniela M., Santos, Silvia R., Martinez, Marina B., Miyaji, Eliane N.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318277/
https://ncbi.nlm.nih.gov/pubmed/22336290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.05706-11
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