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BRCA1-directed, enhanced and aberrant homologous recombination: Mechanism and potential treatment strategies

Despite intense studies, questions still remain regarding the molecular mechanisms leading to the development of hereditary breast and ovarian cancers. Research focused on elucidating the role of the breast cancer susceptibility gene 1 (BRCA1) in the DNA damage response may be of the most critical i...

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Detalhes bibliográficos
Main Authors: Dever, Seth M, White, E Railey, Hartman, Matthew CT, Valerie, Kristoffer
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318103/
https://ncbi.nlm.nih.gov/pubmed/22306997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.11.4.19212
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