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The effect of BRCA1 missense mutations on homology directed recombination
There have been few published analyses of the effects of missense mutations of the BRCA1 gene on BRCA1 protein function. In this study, we adapted a previously described homology directed recombination (HDR) assay to the analysis of the effects of BRCA1 point substitutions on its function in recombi...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2943742/ https://ncbi.nlm.nih.gov/pubmed/20103620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-2850 |
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