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Functional differences among BRCA1 missense mutations in the control of centrosome duplication
We analyzed the effects of 14 different missense mutations in the RING domain of BRCA1 on the function of the protein in the control of centrosome number in tissue culture cells. Whereas 2 of the 14 BRCA1 variant proteins were neutral in the centrosome duplication assay, missense mutations of zinc-c...
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| Publicado no: | Oncogene |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4222025/ https://ncbi.nlm.nih.gov/pubmed/21725363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.271 |
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