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Overproduction of topoisomerase II in an ataxia telangiectasia fibroblast cell line: comparison with a topoisomerase II-overproducing hamster cell mutant.

Ataxia telangiectasia (AT) cell lines are characterised by their hypersensitivity to ionizing radiation and bleomycin, and their failure to inhibit DNA synthesis after DNA damage. A recent report [Singh et al. (1988) Nucl. Acids Res. 16, 3919-3929] indicated that a reduction in topoisomerase II (top...

詳細記述

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書誌詳細
主要な著者: Davies, S M, Harris, A L, Hickson, I D
フォーマット: Artigo
言語:Inglês
出版事項: 1989
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC331807/
https://ncbi.nlm.nih.gov/pubmed/2537956
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