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Migrating fibroblasts reorient directionality by a metastable, PI3K-dependent mechanism

Mesenchymal cell migration as exhibited by fibroblasts is distinct from amoeboid cell migration and is characterized by dynamic competition among multiple protrusions, which determines directional persistence and responses to spatial cues. Localization of phosphoinositide 3-kinase (PI3K) signaling i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Welf, Erik S., Ahmed, Shoeb, Johnson, Heath E., Melvin, Adam T., Haugh, Jason M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317800/
https://ncbi.nlm.nih.gov/pubmed/22472441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201108152
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