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Migrating fibroblasts reorient directionality by a metastable, PI3K-dependent mechanism

Mesenchymal cell migration as exhibited by fibroblasts is distinct from amoeboid cell migration and is characterized by dynamic competition among multiple protrusions, which determines directional persistence and responses to spatial cues. Localization of phosphoinositide 3-kinase (PI3K) signaling i...

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Detalhes bibliográficos
Main Authors: Welf, Erik S., Ahmed, Shoeb, Johnson, Heath E., Melvin, Adam T., Haugh, Jason M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317800/
https://ncbi.nlm.nih.gov/pubmed/22472441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201108152
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