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Comparative assessment of virulence of recombinant vaccinia viruses expressing IL-2 and IL-15 in immunodeficient mice

IL-2 and -15 belong to the four α-helix bundle family of cytokines and display a spectrum of overlapping immune functions because of shared signal transducing receptor components of the IL-2 receptor complex. However, recent evidence suggests a nonredundant unique role for IL-15 in the establishment...

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Autors principals: Perera, Liyanage P., Goldman, Carolyn K., Waldmann, Thomas A.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC33178/
https://ncbi.nlm.nih.gov/pubmed/11296252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.081080298
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