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Autophagy in Premature Senescent Cells Is Activated via AMPK Pathway

Autophagy is a highly regulated intracellular process involved in the turnover of most cellular constituents and in the maintenance of cellular homeostasis. In this study, we show that the activity of autophagy increases in H(2)O(2) or RasV12-induced senescent fibroblasts. Inhibiting autophagy promo...

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Detalhes bibliográficos
Main Authors: Guo, Liujing, Xie, Bushan, Mao, Zebin
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317728/
https://ncbi.nlm.nih.gov/pubmed/22489168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms13033563
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