Critical Role of NADPH Oxidase in Neuronal Oxidative Damage and Microglia Activation following Traumatic Brain Injury

BACKGROUND: Oxidative stress is known to play an important role in the pathology of traumatic brain injury. Mitochondria are thought to be the major source of the damaging reactive oxygen species (ROS) following TBI. However, recent work has revealed that the membrane, via the enzyme NADPH oxidase c...

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Detalhes bibliográficos
Main Authors: Zhang, Quan-Guang, Laird, Melissa D., Han, Dong, Nguyen, Khoi, Scott, Erin, Dong, Yan, Dhandapani, Krishnan M., Brann, Darrell W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317633/
https://ncbi.nlm.nih.gov/pubmed/22485176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034504
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