Critical Role of NADPH Oxidase in Neuronal Oxidative Damage and Microglia Activation following Traumatic Brain Injury

BACKGROUND: Oxidative stress is known to play an important role in the pathology of traumatic brain injury. Mitochondria are thought to be the major source of the damaging reactive oxygen species (ROS) following TBI. However, recent work has revealed that the membrane, via the enzyme NADPH oxidase c...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Zhang, Quan-Guang, Laird, Melissa D., Han, Dong, Nguyen, Khoi, Scott, Erin, Dong, Yan, Dhandapani, Krishnan M., Brann, Darrell W.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317633/
https://ncbi.nlm.nih.gov/pubmed/22485176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034504
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