Estrogen Attenuates Ischemic Oxidative Damage via an Estrogen Receptor α-Mediated Inhibition of NADPH Oxidase Activation

The goal of this study was to elucidate the mechanisms of 17β-estradiol (E(2)) antioxidant and neuroprotective actions in stroke. The results reveal a novel extranuclear receptor-mediated antioxidant mechanism for E(2) during stroke, as well as a hypersensitivity of the CA3/CA4 region to ischemic in...

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Главные авторы: Zhang, Quan-Guang, Raz, Limor, Wang, Ruimin, Han, Dong, De Sevilla, Liesl, Yang, Fang, Vadlamudi, Ratna K., Brann, Darrell W.
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2009
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Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807671/
https://ncbi.nlm.nih.gov/pubmed/19889994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3574-09.2009
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