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Blockade of Fatty Acid Synthase Triggers Significant Apoptosis in Mantle Cell Lymphoma

Fatty acid synthase (FASN), a key player in the de novo synthetic pathway of long-chain fatty acids, has been shown to contribute to the tumorigenesis in various types of solid tumors. We here report that FASN is highly and consistently expressed in mantle cell lymphoma (MCL), an aggressive form of...

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Autors principals: Gelebart, Pascal, Zak, Zoulika, Anand, Mona, Belch, Andrew, Lai, Raymond
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317445/
https://ncbi.nlm.nih.gov/pubmed/22485149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033738
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