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After the bottleneck: Genome-wide diversification of the Mycobacterium tuberculosis complex by mutation, recombination, and natural selection

Many of the most virulent bacterial pathogens show low genetic diversity and sexual isolation. Accordingly, Mycobacterium tuberculosis, the deadliest human pathogen, is thought to be clonal and evolve by genetic drift. Yet, its genome shows few of the concomitant signs of genome degradation. We anal...

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מידע ביבליוגרפי
Main Authors: Namouchi, Amine, Didelot, Xavier, Schöck, Ulrike, Gicquel, Brigitte, Rocha, Eduardo P.C.
פורמט: Artigo
שפה:Inglês
יצא לאור: Cold Spring Harbor Laboratory Press 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317154/
https://ncbi.nlm.nih.gov/pubmed/22377718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.129544.111
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