High Throughput Phenotypic Selection of Mycobacterium tuberculosis Mutants with Impaired Resistance to Reactive Oxygen Species Identifies Genes Important for Intracellular Growth

Mycobacterium tuberculosis has the remarkable capacity to survive within the hostile environment of the macrophage, and to resist potent antibacterial molecules such as reactive oxygen species (ROS). Thus, understanding mycobacterial resistance mechanisms against ROS may contribute to the developmen...

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Detalhes bibliográficos
Main Authors: Mestre, Olga, Hurtado-Ortiz, Raquel, Dos Vultos, Tiago, Namouchi, Amine, Cimino, Mena, Pimentel, Madalena, Neyrolles, Olivier, Gicquel, Brigitte
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540035/
https://ncbi.nlm.nih.gov/pubmed/23320090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053486
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