The Clinical and Prognostic Significance of Activated AKT-mTOR Pathway in Human Astrocytomas

Astrocytomas, the most common type of gliomas, and especially grade IV glioblastomas are “endowed” with strong proliferation and invasion potentials, high recurrence rate, and poor patients' prognosis. Aberrant signaling of AKT-mTOR (mammalian target of rapamycin) has been implicated in carcino...

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Dades bibliogràfiques
Autors principals: El Habr, Elias A., Adamopoulos, Christos, Levidou, Georgia, Saetta, Aggeliki A., Korkolopoulou, Penelope, Piperi, Christina
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2012
Matèries:
Review Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316974/
https://ncbi.nlm.nih.gov/pubmed/22530122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/454957
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