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Characterization of MRFAP1 Turnover and Interactions Downstream of the NEDD8 Pathway

The NEDD8-Cullin E3 ligase pathway plays an important role in protein homeostasis, in particular the degradation of cell cycle regulators and transcriptional control networks. To characterize NEDD8-cullin target proteins, we performed a quantitative proteomic analysis of cells treated with MLN4924,...

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Main Authors: Larance, Mark, Kirkwood, Kathryn J., Xirodimas, Dimitris P., Lundberg, Emma, Uhlen, Mathias, Lamond, Angus I.
格式: Artigo
語言:Inglês
出版: The American Society for Biochemistry and Molecular Biology 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316733/
https://ncbi.nlm.nih.gov/pubmed/22038470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.014407
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