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Expanding the Chemical Cross-Linking Toolbox by the Use of Multiple Proteases and Enrichment by Size Exclusion Chromatography

Chemical cross-linking in combination with mass spectrometric analysis offers the potential to obtain low-resolution structural information from proteins and protein complexes. Identification of peptides connected by a cross-link provides direct evidence for the physical interaction of amino acid si...

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Hlavní autoři: Leitner, Alexander, Reischl, Roland, Walzthoeni, Thomas, Herzog, Franz, Bohn, Stefan, Förster, Friedrich, Aebersold, Ruedi
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316732/
https://ncbi.nlm.nih.gov/pubmed/22286754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.014126
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