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A Framework for Intelligent Data Acquisition and Real-Time Database Searching for Shotgun Proteomics

In the analysis of complex peptide mixtures by MS-based proteomics, many more peptides elute at any given time than can be identified and quantified by the mass spectrometer. This makes it desirable to optimally allocate peptide sequencing and narrow mass range quantification events. In computer sci...

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Main Authors: Graumann, Johannes, Scheltema, Richard A., Zhang, Yong, Cox, Jürgen, Mann, Matthias
格式: Artigo
語言:Inglês
出版: The American Society for Biochemistry and Molecular Biology 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316723/
https://ncbi.nlm.nih.gov/pubmed/22171319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.013185
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