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Optimization of filtering criterion for SEQUEST database searching to improve proteome coverage in shotgun proteomics

<p>Abstract</p> <p>Background</p> <p>In proteomic analysis, MS/MS spectra acquired by mass spectrometer are assigned to peptides by database searching algorithms such as SEQUEST. The assignations of peptides to MS/MS spectra by SEQUEST searching algorithm are defined by...

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Detalhes bibliográficos
Main Authors: Ye Mingliang, Han Guanghui, Jiang Xiaogang, Jiang Xinning, Zou Hanfa
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2007-08-01
Colecção:BMC Bioinformatics
Acesso em linha:http://www.biomedcentral.com/1471-2105/8/323
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