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Optimization of filtering criterion for SEQUEST database searching to improve proteome coverage in shotgun proteomics
<p>Abstract</p> <p>Background</p> <p>In proteomic analysis, MS/MS spectra acquired by mass spectrometer are assigned to peptides by database searching algorithms such as SEQUEST. The assignations of peptides to MS/MS spectra by SEQUEST searching algorithm are defined by...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BMC
2007-08-01
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Colecção: | BMC Bioinformatics |
Acesso em linha: | http://www.biomedcentral.com/1471-2105/8/323 |
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