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Optimization of filtering criterion for SEQUEST database searching to improve proteome coverage in shotgun proteomics
BACKGROUND: In proteomic analysis, MS/MS spectra acquired by mass spectrometer are assigned to peptides by database searching algorithms such as SEQUEST. The assignations of peptides to MS/MS spectra by SEQUEST searching algorithm are defined by several scores including Xcorr, ΔCn, Sp, Rsp, matched...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2040164/ https://ncbi.nlm.nih.gov/pubmed/17761002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-323 |
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