Analysis of IL12B Gene Variants in Inflammatory Bowel Disease

BACKGROUND: IL12B encodes the p40 subunit of IL-12, which is also part of IL-23. Recent genome-wide association studies identified IL12B and IL23R as susceptibility genes for inflammatory bowel disease (IBD). However, the phenotypic effects and potential gene-gene interactions of IL12B variants are...

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Autores principales: Glas, Jürgen, Seiderer, Julia, Wagner, Johanna, Olszak, Torsten, Fries, Christoph, Tillack, Cornelia, Friedrich, Matthias, Beigel, Florian, Stallhofer, Johannes, Steib, Christian, Wetzke, Martin, Göke, Burkhard, Ochsenkühn, Thomas, Diegelmann, Julia, Czamara, Darina, Brand, Stephan
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316707/
https://ncbi.nlm.nih.gov/pubmed/22479607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034349
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