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HIV-1 Nef Enhances Dendritic Cell-Mediated Viral Transmission to CD4(+) T Cells and Promotes T-Cell Activation

HIV-1 Nef enhances dendritic cell (DC)-mediated viral transmission to CD4(+) T cells, but the underlying mechanism is not fully understood. It is also unknown whether HIV-1 infected DCs play a role in activating CD4(+) T cells and enhancing DC-mediated viral transmission. Here we investigated the ro...

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Autori principali: St. Gelais, Corine, Coleman, Christopher M., Wang, Jian-Hua, Wu, Li
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316695/
https://ncbi.nlm.nih.gov/pubmed/22479639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034521
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