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Efficient iPS Cell Production with the MyoD Transactivation Domain in Serum-Free Culture

A major difficulty of producing induced pluripotent stem cells (iPSCs) has been the low efficiency of reprogramming differentiated cells into pluripotent cells. We previously showed that 5% of mouse embryonic fibroblasts (MEFs) were reprogrammed into iPSCs when they were transduced with a fusion gen...

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Bibliografiske detaljer
Main Authors: Hirai, Hiroyuki, Katoku-Kikyo, Nobuko, Karian, Peter, Firpo, Meri, Kikyo, Nobuaki
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316619/
https://ncbi.nlm.nih.gov/pubmed/22479546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034149
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