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Cortactin Tyrosine Phosphorylation Promotes Its Deacetylation and Inhibits Cell Spreading

BACKGROUND: Cortactin is a classical Src kinase substrate that participates in actin cytoskeletal dynamics by activating the Arp2/3 complex and interacting with other regulatory proteins, including FAK. Cortactin has various domains that may contribute to the assembly of different protein platforms...

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Detalhes bibliográficos
Main Authors: Meiler, Eugenia, Nieto-Pelegrín, Elvira, Martinez-Quiles, Narcisa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316595/
https://ncbi.nlm.nih.gov/pubmed/22479425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033662
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