Interferon-α Regulates Glutaminase 1 Promoter through STAT1 Phosphorylation: Relevance to HIV-1 Associated Neurocognitive Disorders

HIV-1 associated neurocognitive disorders (HAND) develop during progressive HIV-1 infection and affect up to 50% of infected individuals. Activated microglia and macrophages are critical cell populations that are involved in the pathogenesis of HAND, which is specifically related to the production a...

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Bibliographic Details
Main Authors: Zhao, Lixia, Huang, Yunlong, Tian, Changhai, Taylor, Lynn, Curthoys, Norman, Wang, Yi, Vernon, Hamilton, Zheng, Jialin
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316554/
https://ncbi.nlm.nih.gov/pubmed/22479354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032995
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