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Protein Phosphatase 1 Dephosphorylates Profilin-1 at Ser-137
Profilin-1 (PFN1) plays an important role in the control of actin dynamics, and could represent an important therapeutic target in several diseases. We previously identified PFN1 as a huntingtin aggregation inhibitor, and others have implicated it as a tumor-suppressor. Rho-associated kinase (ROCK)...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3316545/ https://ncbi.nlm.nih.gov/pubmed/22479341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032802 |
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