Laquinimod, a Quinoline-3-Carboxamide, Induces Type II Myeloid Cells That Modulate Central Nervous System Autoimmunity

Laquinimod is a novel oral drug that is currently being evaluated for the treatment of relapsing-remitting (RR) multiple sclerosis (MS). Using the animal model for multiple sclerosis, experimental autoimmune encephalomyelitis (EAE), we examined how laquinimod promotes immune modulation. Oral laquini...

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Main Authors: Schulze-Topphoff, Ulf, Shetty, Aparna, Varrin-Doyer, Michel, Molnarfi, Nicolas, Sagan, Sharon A., Sobel, Raymond A., Nelson, Patricia A., Zamvil, Scott S.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316495/
https://ncbi.nlm.nih.gov/pubmed/22479444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033797
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