Genetic variation in MME in relation to neprilysin protein and enzyme activity, Aβ levels, and Alzheimer’s disease risk

Neprilysin (NEP), also known as membrane metalloendopeptidase (MME), is considered amongst the most important β-amyloid (Aβ)-degrading enzymes with regard to prevention of Alzheimer’s disease (AD) pathology. Variation in the NEP gene (MME) has been suggested as a risk factor for AD. We conducted a g...

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Main Authors: Miners, Scott, van Helmond, Zoë, Barker, Rachel, Passmore, Peter A, Johnston, Janet A, Todd, Stephen, McGuinness, Bernadette M, Panza, Francesco, Seripa, Davide, Solfrizzi, Vincenzo, Love, Seth, Prince, Jonathan A, Kehoe, Patrick G
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2012
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316445/
https://ncbi.nlm.nih.gov/pubmed/22493749
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