Genetic variation in MME in relation to neprilysin protein and enzyme activity, Aβ levels, and Alzheimer’s disease risk

Neprilysin (NEP), also known as membrane metalloendopeptidase (MME), is considered amongst the most important β-amyloid (Aβ)-degrading enzymes with regard to prevention of Alzheimer’s disease (AD) pathology. Variation in the NEP gene (MME) has been suggested as a risk factor for AD. We conducted a g...

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Autori principali: Miners, Scott, van Helmond, Zoë, Barker, Rachel, Passmore, Peter A, Johnston, Janet A, Todd, Stephen, McGuinness, Bernadette M, Panza, Francesco, Seripa, Davide, Solfrizzi, Vincenzo, Love, Seth, Prince, Jonathan A, Kehoe, Patrick G
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2012
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316445/
https://ncbi.nlm.nih.gov/pubmed/22493749
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