Dynamic reorganization of Eg5 in the mammalian spindle throughout mitosis requires dynein and TPX2

Kinesin-5 is an essential mitotic motor. However, how its spatial–temporal distribution is regulated in mitosis remains poorly understood. We expressed localization and affinity purification–tagged Eg5 from a mouse bacterial artificial chromosome (this construct was called mEg5) and found its distri...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gable, Alyssa, Qiu, Minhua, Titus, Janel, Balchand, Sai, Ferenz, Nick P., Ma, Nan, Collins, Elizabeth S., Fagerstrom, Carey, Ross, Jennifer L., Yang, Ge, Wadsworth, Patricia
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Cell Biology 2012
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315814/
https://ncbi.nlm.nih.gov/pubmed/22337772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-09-0820
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