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TPX2 regulates the localization and activity of Eg5 in the mammalian mitotic spindle

Mitotic spindle assembly requires the regulated activity of numerous spindle-associated proteins. In mammalian cells, the Kinesin-5 motor Eg5 interacts with the spindle assembly factor TPX2, but how this interaction contributes to spindle formation and function is not established. Using bacterial ar...

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Detalhes bibliográficos
Main Authors: Ma, Nan, Titus, Janel, Gable, Alyssa, Ross, Jennifer L., Wadsworth, Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187703/
https://ncbi.nlm.nih.gov/pubmed/21969468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201106149
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