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Reorganization of the microtubule array in prophase/prometaphase requires cytoplasmic dynein-dependent microtubule transport

When mammalian somatic cells enter mitosis, a fundamental reorganization of the Mt cytoskeleton occurs that is characterized by the loss of the extensive interphase Mt array and the formation of a bipolar mitotic spindle. Microtubules in cells stably expressing GFP–α-tubulin were directly observed f...

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Autori principali: Rusan, Nasser M., Tulu, U. Serdar, Fagerstrom, Carey, Wadsworth, Patricia
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173209/
https://ncbi.nlm.nih.gov/pubmed/12235119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200204109
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